Western blot analysis of recombinant β-catenin (G48D) and wildtype proteins. Purified His-tagged β-catenin (G48D) protein (amino acids 1-76, lane 2) and corresponding wild type protein (lane 1) were blotted with anti- β-catenin (G48D) mouse monoclonal antibody (Cat. #26166).
Catalog Number: 26166
Gene Symbol: CTNNB1, CTNNB
Description: Anti-β-catenin (G48D) Mouse Monoclonal Antibody
Background: Beta-catenin (or β-catenin) is a protein that in humans is encoded by the CTNNB1 gene. β-catenin is a subunit of the cadherin protein complex and also acts as an intracellular signal transducer in the Wnt signaling pathway. Deregulation of beta-catenin signaling is an important event in the genesis of a number of malignancies, such as colon cancer, melanoma, hepatocellular carcinoma, ovarian cancer, endometrial cancer, medulloblastoma pilomatricomas, and prostate cancer.
Immunogen: A synthetic peptide from the internal region of β-catenin which includes the mutation of G48D, human origin.
Applications: ELISA, WB, IF, IHC
Recommended Dilutions:
ELISA: 1:1000-1:5000
WB: 1:500-1:2000
IHC: 1:50-1:100
Concentration: 1 mg/ml
Host: Mouse
Format: Liquid
Clonality: Monoclonal
Isotype:
Purity: Purified from ascites
Storage buffer:
Gene Symbol: CTNNB1, CTNNB
Description: Anti-β-catenin (G48D) Mouse Monoclonal Antibody
Background: Beta-catenin (or β-catenin) is a protein that in humans is encoded by the CTNNB1 gene. β-catenin is a subunit of the cadherin protein complex and also acts as an intracellular signal transducer in the Wnt signaling pathway. Deregulation of beta-catenin signaling is an important event in the genesis of a number of malignancies, such as colon cancer, melanoma, hepatocellular carcinoma, ovarian cancer, endometrial cancer, medulloblastoma pilomatricomas, and prostate cancer.
Immunogen: A synthetic peptide from the internal region of β-catenin which includes the mutation of G48D, human origin.
Applications: ELISA, WB, IF, IHC
Recommended Dilutions:
ELISA: 1:1000-1:5000
WB: 1:500-1:2000
IHC: 1:50-1:100
Concentration: 1 mg/ml
Host: Mouse
Format: Liquid
Clonality: Monoclonal
Isotype:
Purity: Purified from ascites
Storage buffer:
Main Products
mAB for Mutated Antibody, Active G Protein, cAMP/cGMP ELA Kits